Malignancy in primary sclerosing cholangitis: Bile duct, liver, and colon
نویسندگان
چکیده
منابع مشابه
Prevention of bile duct cancer in primary sclerosing cholangitis.
Patients with primary sclerosing cholangitis (PSC) have a substantial predisposition to develop bile duct carcinoma. The mechanism is still unclear but the observation that patients with chronic Clonorchis sinensis infection are also prone to cholangiocarcinoma suggests a role for long standing inflammation. However, there is still no effective medical therapy which can halt the progression of ...
متن کاملDe-novo cholangiocarcinoma in native common bile duct remnant following OLT for primary sclerosing cholangitis.
Primary sclerosing cholangitis (PSC) is a chronic, progressive, inflammatory and obstructive disease of the intra- and extra-hepatic bile ducts of unknown etiology. Currently, orthotopic liver transplantation (OLT) is the only definitive treatment for PSC-related end-stage liver disease. However, PSC has been known to recur in the grafted liver. Roux-en-Y hepaticojejunostomy is more commonly pe...
متن کاملIntrahepatic bile duct strictures in a liver allograft recipient mimicking recurrent primary sclerosing cholangitis. Follow-up of a case report.
Sir: Reasons for development of large biliary tract complications after orthotopic liver transplantation (OLT) are varied and include: (a) most commonly, surgical complications from reconstruction of the extrahepatic bile duct [2]; (b) occasionally. recurrence of malignant biliary tract disease [1]; and (c) debatably, recurrence of the original benign biliary tract disease [5,6]. Although a hig...
متن کاملOrthotopic liver transplantation for primary sclerosing cholangitis.
The incidence or diagnostic rate of sclerosing cholangitis is increasing. Because of the lack of effective medical or surgical therapy for patients with end-stage liver disease and sclerosing cholangitis, results with orthotopic liver transplantation were examined. The results of 55 consecutive liver replacements for this disease were reviewed. The 1- and 2-year actuarial survival rates are 71%...
متن کاملMucin-producing bile duct carcinoma arising from primary sclerosing cholangitis: a case report.
A 60-year-old woman with primary sclerosing cholangitis (PSC) and high levels of ALP, gamma-GTP, and DUPAN-2 was admitted to our institution for examination. The patient did not have ulcerative colitis or pancreatic intraductal papillary mucinous neoplasm. Imaging studies revealed atypical dilation of bile ducts in the left lobe of the liver. Repeated cytologic examinations of the bile showed a...
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ژورنال
عنوان ژورنال: Clinical Liver Disease
سال: 2014
ISSN: 2046-2484,2046-2484
DOI: 10.1002/cld.334